marcblank I'm not sure if better focus could be optained by moving further in
Yes. The optical distance from the guide camera sensor (through the prism) to your objective lens will be slightly shorter as you bring the prism closer to the optical axis. (Consequence of the Pythagoras Theorem.)
There is a fine line here. Moving the prism closer to the optical axis will eventually produce vignetting. You want to move the prism as close as possible to the optical axis, as it will produce less star aberrations, too, when sampling a beam close to the optical axis (better star shapes for guiding), but not too close as to produce vignetting.
You can minimize vignetting by rotating the OAG so that the prism is on the long axis of your sensor frame.
Check the documents for your OAG. All OAGs come with screws and such to loosen the prism stem to allow you to push and pull the prism closer and further from the optical axis.
Chen