Helllo,
That's curious, I experienced something quite similar but probably not for the same reasons !
I'm currently doing my best to collimate my brand new TS RC 8, and initially, I had the same problem you detailed.
I've got the same cameras, and also the same Zwo standard OAG, and even though I initially set the highest gain for my 290 MM (with the risk of guiding on dead pixel or artefacts), I had nothing, blank screen, yet, swapping cameras in the ASIair App as you did, the 290MM, I could see stars !
I moved along and finetuning my colliamtion, and I'm now getting very close to a decent image, just the corners I've to work on as I'm probably dealing with a slight tilt and/or BF, not quite sure.
Now, with with a better collimation, I can get a few stars for my guiding camera, but it's very dim !
With my newton I used to get oval shaped stars, but always enough of them, now I get a sort of "blob" very faint, and what is normal, I get fewer stars.
I also improrved the quality simply enabling Bin2 for my guidng camera, what I didn't need to do with my newton 200/800 of course !
When the sky is clear I can guide reasonably well, I managed to get a good 0.40/0.5 last week during 1 hour, but 2 days ago, due to high altitude cloud I guess, it was harder and closer to 1" !
I set my prism so as to position it parallel to the sensor and slightly above when you are looking the front part of your OAG, but it doesn't overlap the sensor, what I've controlled with my flats.
On top of the guiding part, I've also had to struggle with step size for the EAF and find the right setting, it was quite long and iterative, but now it's ok.
The point is that with 1 624 mm of focal length and above for some other telescopes, guiding with OAG is getting a really hard job !
Philippe