I have a Macbook Pro 15" 2013 model fully specked out (I am running Windows 10 via Parallels).
Have a V2 ASI1600MM-C, have all of the latest drivers (been upgrading as they've been coming out) and have never really had any luck at all with the USB3.0 connection. The way that it sometimes processes with the USB2.0 connection also leaves me with some issues that I cannot seem to resolve.
With USB2 I use a USB Speed of 80 and with USB3 I use a USB Speed of 40 (the lowest).
All of the information that I am going to be discussing here comes from Sharpcap although I use MaximDL, SGP, & TSX for image acquisition.
Starting with the USB3. At 16-bit and Full Res it'll run for a few seconds (every frame drops) before the camera driver crashes and it has to be replugged (restarted).
If I run it at 8-bit 1920x1080 (2mp) it'll run at 41.5 fps - 9218 (173 dropped). This is it running at ~86 mb/s with a ~1.8% frame drop which isn't too bad at all.
If I put it into High Speed Mode it'll run at 60 fps for a little while before crashing, considering that it is running at ~120mb/s it is understandable that it'll crash!
The camera driver seems to be able to run at pretty full speed (non high speed mode) when not at full res, some frame drop but doing a pretty good job at being stable. At 4656x3520 8-bit it doesn't crash but it will run at 3fps with 60% frame drop.
So at the moment using the camera under USB3 is utterly useless, just pretty much instantly crashes (thinking mostly when using with MaximDL or TSX).
Now onto USB2. Very stable!
I do however have one "issue" that I don't quite understand. Sometimes with longer exposures 300-400s it can take 30s to "read" the camera after the exposure is complete. Sharpcap can run the camera endlessly at 4656x3520 16-bit endlessly at ~1.1fps (~36mb/s) without dropping a frame. When any other software program (Maxim ect.) reads it an as unbinned image it'll take 1-2 to download the image. If I was to do a 60x300s run it could take up to 30s to "read" each frame and then 1-2 to download that frame from the camera. Doesn't do it with shorter exposures, only longer ones. Around the 60-120s mark it can take maybe 5s to "read" the camera, sometimes instantaneous though.
Just as another side point, this same effect happens with a Compaqu 45 laptop I have with Windows 10 as well so it isn't limited to my Macbook Pro.
I've been fiddling with it on an off for a couple of months now trying to figure out the problem and had no luck at all. One of the reason I wanted the camera was for high download speed which it has as long as I use USB2 and short exposures. USB3 is useless due to near instant crashes and with the "read" delay times it ultimately takes longer than some of the older USB1.1 camera download times.