Thanks Sam. Thanks James, that's interesting.
In the meantime, some preliminary findings from adding power hubs and USB hubs to several of my OTAs:
Regarding USB3 cable length, it seems that 3m might have had a few more issues (speed and stability otherwise) as opposed to 2m. No methodical lab testing though.
However, 2m + powered hub + 1m (the longest I needed) was never a problem when I found the right hub.
The two HUB types I first tried were not good at all, while being from well known brands.
The one I'm using all over now (http://www.tp-link.com/lk/products/details/cat-5688_UH720.html) is slim and compact for mounting, is powered by 12V, helps me obtain the specified framerate with ASI cams, and (opposed to some other hubs) works with all my USB2 devices.
I just recently started using PHD2, so it's a bit tricky for me to see how good the guider cameras are performing when connected through the 1600MMC hub.
So I'm leaning towards a "direct" connection, guidecam to OTA-hub (the UH720 in my case). No issues with the 1600-hub as far as I know, but maybe a tad safer. And much simpler now with a hub fixed at the OTA.
Still would like to hear more of what others have experienced, while connecting the guidecam (typically using OAG) to the 1600MMC hub :)