Hi Sam,
I have the asi1600mm-cool camera. I have uploaded the new latest ASI drivers, with the new option 'Advanced' added for manual user settings.
I am able to change the Gain, Offset and Usb and the default 8-RAW to 16-RAW and exit the driver setup, every things works the way you would expect it to.
When the camera or driver is disconnected and reconnected all the settings that I have changed 'GAIN, OFFSET and USB, stay as is, except for the 16-RAW as it always defaults back to 8-RAW.
Regards
Robin