Have to agree with domtbol. My last night's run is a good example of what can happen.
Remote imaging setup on the roof, cloud rolled in and then out again. Paused the autorun and set high gain bin4 to do a preview and check framing. Forgot to put gain back again, and ended up with many unusable subs.
Gain setting belongs on the preview page as a slider (similar to how it is for the live video), and also as a parameter of an autorun sequence.