Hi
I agree with @StevenEvan comment. With 1.6 and multi star with automatic stars pick up, the guide fails to consider big elongated star (HFD > 5/6) which is kind of normal with OAG on SC telescope and camera such ASI290MM
Binning would be a must for it, and also expose some PHD2 settings, maybe in a well specified advanced settings, in order to tune the logic PHD2 use to pick up the stars
AAP 1.5 worked better in this sense