jayszwo This has been asked here many times before. People have suggested various solutions, like magnetically coupled USB cables, I have one of those but I never had an issue with tangled cables. I have a lot of trees around and I only see a relatively small area of the sky so I never move between targets very far away so this is not an issue for me. But I do see how this could be a problem if you had an open sky and moved around a lot, especially when in unattended plan mode.
It would be of course trivial to keep count of the number of turns the S50 has made and decide to turn in the opposite direction to avoid tangling the cable, even if going the other way is faster. What is funny is that I have seen the S50 actually go the long way around sometimes when moving from target to target, but that seems to be random and has nothing to do with USB cable detangling.