I upgraded to 2.5.1 and took two rigs for a two day session at a dark site:
My first rig consisting of Celestron AVX Mount, Astro-Tech AT102EDL, ASI2600 MC Pro, ASI120MM, ASIAIR Plus, and EAFN worked fine with one exception. During Autorun the display on my iPad intermittently blinked off and returned to the ENTER screen. Pressing enter returned to the Autorun still in progress.
My second rig consisting of Star Adventurer GTI mount, Astro-Tech AT72EDII, ASI2600MC DUO, ASIAIR Plus and EAFN was another story. After polar alignment, I executed a return to home, which over-rotated the rig by 90 degrees to the east. This was consistent throughout the two nights. The GOTO function always tried to slew to a target the wrong way, resulting in hitting end of travel multiple times, even when I manually slewed close the target first. Guiding was terrible with multiple error messages "no suitable guide star found" and some error about "lock screen". I finally had to increase the gain on the guide sensor to around 200 to get it to find a guide star. It also failed to execute meridian flips. It also had the problem of blinking off and going to the ENTER screen, even though I use an android phone with this rig. After returning home, I downgraded this rig to 2.4.2 and everything worked normally as it had before the upgrade.