Not sure if I mentioned this but whenever the issue appears and the main camera gets disconnected, the EFW filter wheel remains connected all while being attached through the main camera hub. This would speak against a physical problem IMHO. Again I will try with a different cable and will report the observed results.
@tech@zwo - as a workaround it would be great if a future release of the ASIAIR Pro firmware could reconnect the camera without manual configuration or, at least, keep Cooling active by default. One of the most costly (time-wise) parts of those pesky disconnects is that Cooling goes off and it takes a few minutes after the manual reconnect and the manual switching on of Cooling before the temperature is back to the required value (e.g. -20°C).