BenBret-1 it always happened while saving the file.
Is power fed differently when you use ASIstudio vs when you use ASIAIR? Are you running at least 18 AWG wires for the power?
By the way, if you are feeding ASIAIR and the camera from two different power supplies, make sure to bond the ground returns (the negative leads) of the two supplies together with a heavy gauge wire.
If I were you, I would set the ASIAIR up completely stand-alone, with only power and camera connected to it (and Ethernet, if you use Ethernet instead of WiFi). No mount, no dew heaters, no guide camera, not EFW or EAF, and nothing connected to the ASIAIR power output. Similarly, nothing connected to the camera but the USB 3 port and power. At warmer room temperature. See if you can get a stable image capture.
If it is stable, you can then slowly recombine your original setup back, changing only one component at a time (including moving it from indoors to outdoors), to see which one leads to instability.
By the way, another thing you can try is to use a USB 2.0 cable (the one where the Type B end does not have the USB 3 bulge). See if that is more stable. If that works, it won't really be that slow with the small IMX533 sensor. Sorry I forgot to mention is as a possible work around.
Good luck,
Chen
