cyberdanny And EQ mode magnifies this situation. One suggested solution/workaround is to use 1.1 Framing. This will cause the sensor to shift slightly averaging out the noise. In ALT/AZ mode, since the object is actually rotating on the sensor this accomplishes the same averaging.
Credit for this workaround goes to other users on Cloudy Nights. It worked quite well for me on a two hour EQ exposure of M81/M82....