Kevin_A
Hi Kevin. I almost had the exact same thing happen to me with my AAP. I left my scope out parked in home position for at least 4 nights straight. But I had problems...towards the end of PA, all of a sudden I would get "plate solve failed" messages....but I did not get those messages at the begining of PA.(?) PA finally worked after several tries, but easily lost over an hour of clear skies.
The following nights, I skipped PA altogether and went directly for my targets....and it centered them perfectly. But then had guiding issues afterwards. And on my last night, I had the exact same thing happen to me in which my target drifted out of center...and to the right of the screen....and it was M33 🙂
Over the weekend, I contacted ZWO support and sent them my logs. They said they would get back to me by today.
Best of luck!
Jeff